1. Skin aging
      Skin, protects us from the pathogen infection, is the greatest immune organ of human.

            Do you like such skin?

     
    The changing of life style, environmental factor or diet habit is possible to induce skin aging, ex.:
     - excessive carbohydrate or bad fat
     - air pollution
     - free radicals
     - UV light
     - smoking
     - staying up late
     - hormone decrease or cell death

Aging always revealed on skin; wrinkles, streak across skin unintentionally.

Skin caring should be taken notice daily.

2. Stem cell
It is separated into two types:
1) Embryonic stem cells
     It exists in blastula of former embryo, and the totipotent stem cells can differentiate to cells of all tissues, organs and propagation.

2) Somatic stem cells
   Somatic stem cells exist in the mature tissues and organs. They are the progenitor cells with differentiating capacity to repair and renew the tissues. They stay mainly in special niche to react with stromal cells. The stromal cells secret a serial of growth factor or ligand to regulate renew and differentiation of stem cell.    

3) Stem cell activating factor
      Stem cell starts to differentiate and repair tissues as activating by following factors :
      (1) PDGF-BB => Platelet derives growth factor to stimulate fibroblast renew and synthesize collagen.
      (2) SCF => Stimulate stem cell to move and increase.
      (3) ICF-1 =>The important growth hormone of human tissue cell.
      (4) TGF-b3 => Enhance injury healed and decrease scar.
      (5) EGF => Enhance epithelium renew.
      (6) VEGF => Enhance epithelium of blood vessel renew.
      (7) bFGF => Enhance fibroblast to grow.

4) Developing potential
       BioWare accumulates experiences of molecular technologies for years to study various growth factor which activates somatic stem cells for repairing injured or aged skin and recovering young, beauty and blonde skin.