Research items

Acinetobacter baumannii detection


 

1. Superbug


    As antibiotics continue to be abused, more and more bacteria develop the drug-resistance, and results in ineffective treatment of patients and serious deaths. Superbugs are bacteria that resist many antibiotics, and almost all antibiotics have no effect to them. There are ten dangerous drug-resistant bacteria currently.




2. The generation of drug resistance

 


       In the bacterial population, some are resistant to drugs. As the antibiotics completely kill the non-resistant bacteria, the residual drug-resistant bacteria will flourish and share the resistance gene to the non-resistant bacteria, generate drug resistance, resulting in the failure of the antibiotics.


3. What is Acinetobacter baumannii?
   
Acinetobacter baumannii is a common strain in hospitals. The main route of infection is contact infection, which is transmitted through the hospital's equipments. Research reports show that gloves, tap water, intravenous fluids, monitors, mattresses, staff hands, respirators, etc. Many reports indicated that are associated with nosocomial infections. In recent years, the abuse of antibiotics has caused multiple resistances of Acinetobacter baumannii, and even strong antibiotics are difficult to eliminate. There is almost no medicine to kill them.

4. Terror of Acinetobacter baumannii
1) Objects

   A patient with weak immunity or defects.

2) Symptom

   Acinetobacter baumannii causes bacteremia, sepsis, pneumonia, meningitis, etc., and it is very severe that even cause death with a fatality rate between 20~50%.


5. Prevention of Acinetobacter baumannii

    To prevent the occurrence of large scale nosocomial infections, it is necessary to strengthen environmental disinfection and advocate medical staff to wash their hands, wear gowns, and completely isolate infected patients. Therefore, it is also necessary to strengthen the detection of Acinetobacter baumannii before the patient is admitted to the intensive care unit or the general ward.

6. Detection method development
   
BioWare has developed a special primer for Acinetobacter baumannii through genetic engineering technology, and used it as a detected target. After mixing with buffer, it can analyze the distribution or quantity of Acinetobacter baumannii.



 

Acinetobacter baumannii detection methods :
--Short detection time, about 3-4 hours--
--It is specific, free from interference of environmental bacteria signals--
--Reduce testing and medical costs--
--Reduce environmental risks--